Description

What Is Ipamorelin?

Ipamorelin is a synthetic peptide—a short chain of five amino acids (called a pentapeptide)—designed to mimic the body’s natural “growth signal.” It belongs to a class of compounds known as Growth Hormone Secretagogues (GHS), which means it helps your body secrete more of its own growth hormone (GH) rather than supplying GH directly.

Ipamorelin works by binding to a specific receptor in the brain and pituitary gland called the Growth Hormone Secretagogue Receptor (GHS-R)—also known as the ghrelin receptor. Ghrelin is often called the “hunger hormone,” but it also plays a major role in growth, repair, and energy balance. When Ipamorelin activates this receptor, it triggers a natural, pulsatile (wave-like) release of growth hormone, similar to how the body releases GH during deep sleep or after exercise.

One of the main reasons Ipamorelin attracted scientific interest is its selectivity. Unlike older growth hormone–releasing peptides, Ipamorelin stimulates GH release without significantly increasing cortisol or ACTH (stress-related hormones). This makes it a clean research model for studying how GH and IGF-1 (Insulin-like Growth Factor 1) affect bone, muscle, and metabolism—without the confounding effects of stress hormone spikes.

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Introduction to GLP-3RT

GLP-3RT is an experimental peptide analog designed to explore receptor activity within the glucagon-like peptide (GLP) family. While GLP-1 and GLP-2 have been widely studied for their roles in glucose regulation and intestinal growth, GLP-3RT is a synthetic construct developed for receptor-binding research, metabolic signaling studies, and structure–function analysis.

Currently, GLP-3RT remains a laboratory-only research tool, intended to help investigators understand how structural modifications in GLP-family peptides influence receptor specificity, intracellular signaling, and pharmacokinetic behavior.

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